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Source: Logical Therapeutics, IncLogical Therapeutics, a Waltham, Mass. Based biopharmaceutical company announced which positive data from a Phase I / II clinical trial evaluating the gastrointestinal safety of his investigational drug LT – NS001, LT in a new class of bio – enabled prodrug treatment of treatment of chronic arthritic conditions of. In the study, subjects lived LT – NS001 , a 78 % reduction in the rate stomach ulcers and is less digestive duodenum erosions, when they comparison with volunteers Naprosyn) . The LT – NS001 prodrug is unique among non-steroidal anti-inflammatory drugs , pharmacologically inactive how it a COX inhibitor of the GI tract, but rather once added in the the bloodstream quickly is converted rapidly to naproxen. LT – NS001 has been developed lessen the GI reliability risks in connection with NSAIDs. The results were presented here on the American College of Gastroenterology announced which Annual Scientific Meeting of and presented by Jay L. Goldstein , a professor of medicine from the University of Illinois in Chicago, Who was lead investigator the study. The positive results this study challenge of which conventional wisdom about NSAID-induced the gastrointestinal violations, physicians generally believe of the trial were distributed by the systemic exposure to the medicinal product These study are shows that the new mechanism of NSAIDs, namely a biological – activated prodrug technologies can be a significant degree of improvement in GI certainty, and this can be surprising at many clinicians said Peter A. CEO of Logical Therapeutics. This study takes we a step of closer to meeting of a significant unmet medical need for a NSAID used with an improved GI toxicity profile and we are looking forward which further clinical development from LT – with a with our next study is start at a later point this year. .

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