And manifests as impairments in short-term memory.

Aspartic acid in hippocampus might be biomarker for predicting occurrence of cognitive dysfunction Postoperative cognitive dysfunction is the deterioration of cognitive performance after anesthesia and surgery, and manifests as impairments in short-term memory, concentration, language comprehension, and social integration skills. Previous studies show that the occurrence of postoperative cognitive dysfunction is affected by many factors, including advanced age group, low educational level, pre-existing cognitive impairment, alcoholic beverages abuse, and severity of coexisting illness. Nevertheless, the real cause for postoperative cognitive dysfunction is unclear still.The findings are published in the journal Vaccine In light of the initial findings, extra assays on volunteers’ samples were done by researchers at the University of Alabama at Birmingham, independently confirming the presence of long lasting and top quality T cell responses against HIV antigens. Results from this confirmatory study are available on the web in the Journal of Virology . In this phase I clinical trial, sponsored by the National Institute of Allergy and Infectious Diseases , volunteers 1st received three shots of a DNA vaccine which expresses defensive antigens from the HIV virus, followed by two shots of a protein vaccine whose elements matched those contained in the DNA vaccine. The record in Vaccine may be the first scientific article when a DNA prime-protein boost combination vaccination method is tested in humans for HIV vaccine development.

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