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Which creates the cancer from just a handful of missteps.

This is surprising. Most cancers have a lot of changes,’he explained. AML accounts for about 20 % of childhood leukemia. This year will be diagnosed in about 500 U.S. Children. About 60 % of young AML patients at long-term survivors.. Of AML,hensive look at Rare Leukemia Finds Relatively few genetic changes launch diseaseThe comprehensive analysis yet of the genome of childhood acute myeloid leukemia was only a couple of mistakes in the genetic code, which creates the cancer from just a handful of missteps, according to new insights from St. Jew Children Research Hospital. The research appears in the July 27 online issue of the Proceedings of the National Academy of Sciences.

For this study, researchers analyzed leukemia cells from 111 St. Jew AML patients The researchers foundst common subtypes of the disease. The scientists used a variety of techniques to make the changes, including single nucleotide polymorphism microarrays to catalog genome-wide regions of DNA gain or loss, as the copy number changes are announced diagram. To identify point mutations and DNA researchers re-sequencing of 25 genes that are mutated in adult AML usually performed. Point mutations within a single chemical change in the molecular building blocks of DNA. Continue reading

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