High blood pressure is an important cause of cardiovascular disease.

High blood pressure is an important cause of cardiovascular disease. Earlier studies have shown that it is extremely difficult to identify genes the blood pressure the blood pressure, and partly because of the blood pressure by non – genetic factors, such as exercise and the intake of salt in food and partly is impaired because genes to that work together to blood pressure blood pressure.

The areas of the genome , which were identified in the study contained several genes that are likely to play a role in the regulation of blood pressure. The CYP17A1 gene on chromosome 10q24, for example, play a central role in the biosynthesis of glucorticoid hormones that affect the metabolism of salt. In another region on chromosome 1p36 genes it for two peptides with sodium expulsion effects. A lesser known gene in this area CLCN6 encodes a chloride channel in the neurons not associated with the not associated with the regulation of blood pressure, and in a region on chromosome 17q21, the phospholipase gene PLCD3 what is important for signaling in the smooth muscle..Known role in blood coagulation play a role in blood clotting and other cell functions is well crucial for the correct sperms formation in mice, according to scientists of the University of North Carolina at Chapel Hill School of Medicine.

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